mìsula® magazine


INCREASING HGH AND TESTOSTERONE TO BEAT AGE EFFECTS

HGH (Human Growth Hormone) is the master hormone in your body. It enables your liver to produce Insulin Growth Factor IGF1 that controls all growth processes in your body. After you reach adolescence, HGH production begins waning off. This sets into motion the aging process. Most men also experience a drop in their testosterone levels after the age of 30. Reducing testosterone and HGH can lead to loss of lean muscle, weight gain, belly bulge, reduced or diminished libido, sexual dysfunction, appearance of wrinkles and fine lines etc. 
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FRAME’S PRO-AGEING APPROACH TO COUNTER HYPERPIGMENTATION:

Dark spots on the skin are not all the same. They can vary in shape, size, color and type. While they do not create health problems or side effects, as we grow older, dark spots age us significantly. Even the most common types of spots have different causes. Among the most typical causes are:
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FRAFRAME® SKINCARE WITH TARGET ACTION IN TERMS OF FIRMING AND LIFTING

Of all the products in our range, the R5 (Extreme Restorative Anti-ageing Satin Serum) has the most targeted firming and lifting action that specifically works to plump, hydrate, and tone the skin. It is effective in diminishing wrinkles on the face and eye contour area. R5’s targeted action is due to a particularly high quantity of pure Hyaluronic Acid, one of the most important biopolymers used to retain water and moisturize skin.
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MUSCLE MASS, METABOLISM AND MATURITY

There's a distinct relationship between muscle mass, metabolism, and aging. Basically, the older we get, the more we lose muscle mass, and the loss of muscle means a slow-down of metabolism. The result is obesity, and numerous health risks abound. Those deleterious risks include high blood pressure, high bad cholesterol, low good cholesterol, type-2 diabetes, poor eye-sight, and higher risk of cancer, heart disease, or stroke. After the age of twenty most individuals lose basic metabolic rate of approximately three percent every ten years.
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THE AGELESS GRACE

The Earth goes around the Sun. This is a well-known fact. One other hard fact is, that we are continuously aging. Are we aging graciously? Or, with pain and disease? Is there a profound solution, that has existed from our ancient history, to this problem? It is time to delve deeper to understand, the deep treasures of the past. Geneticists have discovered that cell damage is the primary cause for cell death and eventually us growing old. What this means is, how we use our bodies, determines our longevity.
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THE TOP TEN RULES TO BE A HAPPY AND HARMONIOUS PERSON

Psychological barriers, a negative mindset, and a narrow mind don’t let us live happy lives. To break this vicious circle, many people read classical, science fiction, and religious books. A famous psychiatrist, Mikhail Efimovich Litvak, wrote a book where he describes the most common, in his opinion, psychological barriers that don’t let us live happy and healthy lives. You can think about these while driving or whenever you have some free time to let your mind roam.
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HOW TO TONE YOUR FACIAL MUSCLES

Exercising your face sounds like an odd subject to discuss, right? Not if you think about it. Your face has approximately 50 muscles. Just like every other part of your body, these muscles should undergo a regular workout to stay fit and toned. This is crucial in the journey to preserving, or restoring, a youthful appearance. Open your mind and pretend that, instead of the face, this article was written about abs (or whatever body part you prefer). What happens when you exercise those muscle groups? They begin to firm, lifting and toning - not just the actual muscles - but the skin that covers the area as well. This is the exact result you will get from exercising facial muscles.
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FAST AND POWERFUL PRO-AGEING STRATEGIES

Everybody wants to feel and look as young as is possible. You truly have to take a look at anti aging from several perspectives. Part of staying young is related to your attitude towards life. Other factors include the appearance of your skin and having the proper weight. If you'd like to feel and look much younger than you are, keep the following strategies in mind every day.
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SUNSCREEN AND ANTI-AGEING

 Today, we know that the sun can damage our skin immediately and long term. To help understand why this is important and what happens, you must understand the type of UV rays. There are 2 types of UV rays that reach the earth and damage skin: UVB Rays and UVA rays.
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EXERCISE AND COGNITIVE AGEING

The primary concern with motor performance affecting movement abilities of older individuals. There have been numerous studies conducted on the slowing motor functions as we age and it's often been assumed it's because of the decreasing general motor control we have as we age. A study conducted by Vercyuyssen, Reynolds, Hancock, and Quilter in 1994 studied the variations in simple and choice reaction time in individuals from age 20 to age 90. The results of this study suggest a marginal slowing in simple reaction time with age, but a dramatic slowing in choice reaction time.
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THE MAIN THINGS THAT ACCELERATE AGEING OF THE SKIN

The face and hands are always exposed, which is one of the main reasons that they are the first parts of our body to show signs of ageing. Whether they are facing the cold, wind and rain of winter or the heat of the sun in summer, all types of weather can affect the skin. And it's not just the weather; the pollution and car exhaust fumes can also play a part in ageing our skin. Lots of things accelerate the ageing process of the skin:
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MELATONIN: THE SUPPLEMENT YOU TAKE BEFORE BED DOES TOTALLY AWESOME THINGS FOR YOUR SKIN

The conversation around topical melatonin for skin has been buzzing amongst dermatologists for a while now, and lately it’s started to hit the mainstream by popping up in products. And, if preliminary research is to be believed, it may be just as good for your skin as it is for your REM cycle. “Melatonin is a hormone produced in the skin as well as in the body,” explains Austin-based dermatologist Ted Lain, MD, noting that it tends to be mostly concentrated at night.
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WHEN IT COMES TO VITAMIN PILLS IS NOT ALWAYS BETTER…

Some vitamins are simply pointless and won't improve your health. Some vitamins may be dangerous at high doses. Vitamins and minerals are essential to health, but that doesn't mean that megadoses will keep you out of the hospital or make you live longer. Some may be harmful. In most cases, it's preferable to get these nutrients from a balanced diet. High doses of certain vitamins and minerals may be appropriate for certain people, though. Talk to your doctor about supplements if you are a woman of childbearing age, are a vegetarian or vegan, have limited exposure to the sun, are an athlete in training, or suspect for any reason you may be malnourished. Here's the lowdown on eight common supplements — most of which are vitamins you probably don't need.
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WHAT IS THE PDO THREAT FACELIFT

All of us are fighting with time, but we are still on the losing side. The reflections of the hours, days, months, years are the current state of our body. Not just the way we feel exhausted and tired, which is always connected to how we look. The lack of self-confidence and the feeling of underachieving your visual expectations can cause side effects and serious conditions such as depression and lead to chronic disappointment in everyday life. The decrease in your happiness will affect how well you perform throughout the day, and leave you feeling even more down than before.
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SHOULD YOU EXFOLIATE IN WINTER ?

It's cold and windy, and you probably have more than a few flaky patches on your face. But while you'd love to slough them off and reveal those under-layers of smooth, polished skin, you might find yourself wondering, Is it actually OK to exfoliate in winter, or will I totally dry out?
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HOW TO GET RID OF BACK ACNE

Most people have relatively well-formed opinions about how how to handle the average face pimple. Whether you’re devoted to retinols, double-cleanse like your life depends on it, or resort to popping, you likely have a game plan or two developed back when puberty first made your hormones go haywire. Less talked about however, is body acne, especially when it sets up shop on your back. Bacne happens in part because acne can happen anywhere on your body where sweat glands are present. But how do you treat it, especially if it crops up in hard-to-reach places? And how much does your gym schedule actually contribute to your skin woes? We tapped four pros for their tips.
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KIM KARDASHIAN’S BATTLE WITH PSORIASIS

A slew of powerful medications can help control psoriasis, but your most powerful weapons against the condition may be some simple lifestyle changes. From eating right to de-stressing to honing your beauty routine, how you live your life can affect psoriasis symptoms for the better. The best part? Many of these same lifestyle measures will boost your overall health. Here's how to take control over your psoriasis by making smart choices in your daily life.
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A NEW THERAPY CURES CANCER WITH JUST ONE INJECTION (?)

Chemo and Radiotherapy can be effective treatments for cancer. The downside, of course, is a range of difficult side effects experienced during treatments. Fortunately, a type of treatment that aims to harness the immune system to combat cancer (called immunotherapy) could completely change the way cancer is treated in the future.
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HUGE RESEARCH REPORT SAYS THAT COFFEE INCREASE LONGEVITY

You might be one of the millions upon millions of people who enjoy a cup of morning coffee every day to start things off right. You may also need the mid-morning pick-me-up brew, or a coffee break with co-workers before, during or after lunch, or any other time during the day. Maybe you even enjoy a smooth cup of decaf in the evening after the long day is finished. Whether your coffee habit constitutes one drink a day or several, you are not alone in a routine that so many people find not only enjoyable but necessary to get through the day.
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EVERYTHING YOU NEED TO KNOW ABOUT VITAMIN “D” SUPPLEMENTS:

You need vitamin D to help absorb calcium for strong and healthy bones and some studies have even shown that it may have an effect on your mood, weight, and overall health. But just because there are some big benefits to vitamin D doesn't mean you should go grab a bottle off the shelf at your local drugstore. It's important to understand a few things about supplements before starting a regimen.
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COCONUT OIL AND OTHER NUTRITIONAL ERRORS

A 50-minute German lecture becoming a viral hit on YouTube might sound unusual, but the title of the talk by Karin Michels, the director of the Institute for Prevention and Tumor Epidemiology at the University of Freiburg and a professor at the Harvard TH Chan School of Public Health, has caused a bit of a stir online. During the lecture, titled "Coconut Oil and other Nutritional Errors," Michels has made herself very clear with regard to dietary recommendations, and underlined that coconut oil is not healthy.
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ALKALINE VERSUS ACID: WHAT TO EAT FOR HEALTHIER SKINCARE ?

For most of us, leading a more balanced life ranks at the top of our priorities. But balance doesn’t only pertain to external factors like stress, work, and your personal life. Balance within your body, otherwise known as pH, is extremely important to your overall health. You could say achieving it is one of our most important balancing acts. What’s your ideal balance?
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HIGH PRESSURE MAY BE AGGRAVATED BY ZINC DEFICIENCY

Zinc deficiency induces hypertension by promoting renal sodium reabsorption, published ahead of print in the American Journal of Physiology—Renal Physiology. Lower-than-normal zinc levels may contribute to high blood pressure (hypertension) by altering the way the kidneys handle sodium. The study is published ahead of print in the American Journal of Physiology—Renal Physiology. Zinc deficiency is common in people with chronic illnesses such as type 2 diabetes and chronic kidney disease.
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AGEING DOESN’T HAVE TO BE A PAINFUL PROCESS !

Some people don't know how to cope with the effects of growing older. This article will give you some great advice on aging gracefully. You can also find out ways on how to prevent aging and even control the speed you age. Always learn new things.Whether it is through a course at the local college about computers or a simple crossword puzzle, stay on your mental game and keep your mind young. Don't dwell on the numbers in your life. Personalize your home to make it your own special touch.
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WHAT CAUSES AGEING & WHY ANTI-WRINKLE FACE CREAMS ARE A HIT AMONG WOMEN AND MEN:

You cannot prevent aging, but you can prevent the onset of the most obvious signs of aging like fine lines and wrinkles. An effective and constant attempt at prevention can help you look younger than your real age. The approach to preventing wrinkles involves, among other things, using effective anti wrinkle face creams. What Causes Aging? Women and men from the aging demographic have been trying to find the best anti aging product for ages. Over the past few decades, the demand for anti aging formulations has been growing with every one wanting to stay young.
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THE AGEING BRAIN (ARCD)

Have you noticed small perceptual changes as a result of your aging brain? We are all concerned about losing our mental abilities as we age. It's no surprise that the rate of decline is correlated to certain aspects of our physical health. Cognition is a broad term that includes comprehension, memory, judgment and reasoning. This includes learning, decision-making, and language skills. These are skills of intelligence that we have used all our lives and taken for granted. Cognitive impairment can occur at any age, but I'm referring to Age Related Cognitive Decline or ARCD.
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INTRODUCING YOU THE M5.1 & M5.2 MEDITERRANEAN ESSENTIAL OILS WITH  D3 – NANO MIST DIFFUSER FROM FRAME®

Essential oils are extremely prized substances whose extraction is an ancient art. Also known as etheric oils, they are natural products, obtained from plant material rich in essences belonging to medicinal herbs and plants, commonly known as aromatic herbs. Although they are called “oils” their molecular structure and texture is quite different from normal vegetable oils used in cooking. Essential oils have quite a complex composition and they contain the most prized substances of the plant, found in minuscule droplets in the petals of flowers, the peel of fruit, the resin and bark of trees and the roots of aromatic herbs and plants.
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IMPORTANT HABITS FOR MEN OVER 50:

According to two highly regarded medical doctors, many men over 50 fool themselves into thinking that health will follow them to one-day when they’re less busy. Healthy-aging experts revealed seven important habits that men over 50 are not doing to improve their health:
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EMBRACE VEGAN BEAUTY WITH FRAME® COSMETICS

FRAME® COSMETICS continues to lead the wave of vegan beauty brands to deliver safe and effective Pro-Ageing solutions and services inspired by the free and easy Mediterranean spirit. Aiming to actively celebrate the cycles of life through its offer, FRAME® COSMETICS continues to dedicate R&D to enhancing its range of cruelty-free, vegan beauty products — proving that health and happiness go hand-in-hand when it comes to sustainable, long-lasting beauty solutions.
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DOES BOTOX HURT ?

In the past two decades botox has become one of the leading non-invasive cosmetic options for smoothing wrinkles, and reducing the signs of age. Many people (especially women in the 40-65 age group), are happy to pay the cost to erase deep creases and wrinkles, but they are concerned about possible pain during treatment. So one of the most common questions asked by botox cosmetic newbies is - Does botox hurt? and they also want to know- How does it work?
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LITTLE KNOWN SECRETS ABOUT ANTI-AGEING CREMES

Aging is a natural process that all people have to go through, whether they like it or not. It is a normal stage where some functions of the body's parts will diminish or lessen. Using the eyes, you can easily tell if an individual is already old or not by just looking at his or her skin. When you see some signs of wrinkles in the forehead and in the hands, you can guess the age of the person. However, not all signs of aging that you see on the skin correctly correspond to the person's biological age because there are people who already have wrinkles even if they are still in their late 20's or early '30s.
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BASIC SKINCARE AND GROOMING FOR ASIAN MEN:

It is not uncommon to see women with a vanity table (or cabinet) filled with skincare products, and a rather complex skincare routine. We can’t say the same about men in Singapore and across Asia (with maybe the exception of South Korea). Most men we know have a grooming regime, which includes basic ones like brushing your teeth and showering (we hope!). But we’ll be hard-pressed to find an Asian man who uses anything more than a cleanser – just ask your dad, brothers, or friends!
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WHAT MAKES RETINOL (VITAMIN A) EFFECTIVE FOR SKIN CARE:

Most anti-aging products available in the market today contain retinol because it is considered as one of the best ingredients for reducing wrinkles, fine lines and other visible signs of aging. The purest form of vitamin A, retinol is a potent antioxidant that works to protect the skin from damage caused by free radicals, substances that contribute to skin aging such as pollution, sun damage and other environmental stressors. Not only that, retinol also helps generate cell growth and repair damaged cells. The result is younger looking skin, smooth, soft and free from wrinkles and fine lines.
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THE MOST IMPORTANT CHARACTERISTICS OF PEOPLE WHO ARE AGEING WELL

No one is immune from getting older. So we might as well enjoy life while we can, with good health and happiness. And, like my father always says, "It's better than the alternative." For many of us the biggest problem with aging is the negative impact it can have on our quality of life. We just can't do the things we were able to do when we were younger. Many see this as an obstacle too big to conquer and they give up. Some spend the rest of their days watching television, struggling up the stairs, and taking three naps a day. They're "too tired" to do anything else. What other option do they have?
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DELIVERING UNIQUE AND SPECIFIC FORMULAS FOR EACH MARKET AS WELL A PERSONALIZED SERVICE

Unlike other brands, FRAME® tweaks its formulas for each market, as such, the same products sold in different countries will differ. The company has developed unique specific formulas that are suitable for North and South Europe; North and South America; Middle East; Eurasia; Southeast Asian; Northern China, Japan and Korea. This, because all this regions differ not only in terms of climate, but also in terms of the genetics of their inhabitants. Additionally, the brand also offers a personalization for those seeking individualized formulas.
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HOW TO MAKE HOMEMADE MANICOTTI:

Similar to the Italian “cannelloni”, manicotti can be extruded in tube form, or rolled from sheets of dough. The traditional Mediterranean version of the manicotti recipe uses a crêpe instead of pasta tubes to contain the filling, which is similarly covered in sauce and baked. These tender manicotti are much easier to stuff than the purchased variety. Manicotti is a great dish if you’re planning a dinner party. Serve it with a crisp salad and some bread on the side if you wish.
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Frame® Protective And Purifying Creams With Antioxidant Action:

In the world of beauty and well-being, the word “antioxidant” often comes up. But what are really these actives? And what are they used for? One of the theories used to explain aging is the oxidative stress theory, in which very reactive molecules linked to oxygen damage our most vital molecules, such as DNA or cell membrane components, at all times. These highly reactive molecules are called free radicals or reactive oxygen species (ROS). Although ROS can be harmful, they are also essential because of their important biological functions.
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The Role Of Antioxidants In Cosmetic Formulations

Antioxidants are valuable allies to help the skin fight against free radicals, factors of premature skin aging. Using a cream that contains antioxidants is therefore contributing to the health of the skin. This is especially interesting for people who smoke and who know the effect on the quality of the skin, or those who are often exposed to the sun or in a city with a high pollution rate. Moreover, the Frame® antioxidant active ingredients guarantee an effective protection without fragilizing, and free of ingredients that could be harmful to any type of skin.
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What Can I Do About My Aging Skin When I’m Over 50 ?

If you are over fifty years of age, a proper skin care program becomes more important than ever to find the best anti aging skin care regimen that will protect your skin from the disastrous effects of the sun, environment, and bad habits like smoking and excessive drinking. The sun is the biggest culprit that causes visible aging. The sun's UV rays have the ability to invade the skin and change the structure of the skin cells. Anti aging skin care products are designed to prevent and reverse these effects. The best anti aging skin care product is an effective wrinkle cream or serum.
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The Application Of Sunscreen Is Essential But Not Sufficient

In a world where people travel a lot and where sports and outdoor activities are very popular, prolonged exposure to UV radiation is becoming more and more frequent. The efficacy of these protective creams is limited by the frequency of use and application by the user. Moreover, their spectrum of protection is often incomplete. Currently, sunscreens are made up of so-called “filtering” molecules that are efficient only in specific UV spectrums such as UVA or UVB.
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The Importance Of Ingredients Present In Anti-Aging Wrinkle Creams

Ingredients are always considered to be an essential part of every preparation whether it is your favorite dish or an anti-aging cream. One of the most common problems among women which come up with the growing age is wrinkles. Wrinkles are considered to be the primary signs of ageing. The very thought of wrinkles seems to be scary for most of the women due to which they generally start using a distinctive anti-aging wrinkle cream. However, any significant wrinkle cream only proves to be effective when it contains useful ingredients.
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Why Pomegranates May Help You To Live Longer:

Scientists from claim that the humble pomegranate may hold the secret to a longer and healthier life. Researchers from the Ecole Polytechnique Federale de Lausanne, say that pomegranate contains what they call a 'miracle' ingredient that strengthens ageing muscles and adds years to lifespans. That is an interesting claim, so it is worth exploring to find out what is behind it. The scientists conducted experiments using worms and mice. The findings they say are "nothing short of amazing".
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How To Treat Acne And Wrinkles When You Have Both ?

When you have acne and wrinkles, finding a skin care routine that tackles both can be difficult. Do you use products labeled as anti-acne or labeled as anti-wrinkle? The answers are easier than you think-if you know how to find the right products! Acne breakouts or wrinkles are challenging enough when you're dealing just with one or the other. But, when you're struggling with both, treating them can be frustrating and confusing. Here’s a step-by-step plan to help you fight acne and wrinkles so you can find your skin looking radiant, clearer, and smoother in just a few days!
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When To Start Using Anti-Aging Creams ?

The use of beauty products such as anti-aging creams has been in prevalence for several decades. As time has progressed, these products have become more advanced because of the huge number of researches made in the concerned field. These products keep evolving as a result of changing environmental dynamics. Modern life is overly stressful, and hence, aging comes to us much before than expected. Erratic lifestyle, lack of proper nutrition and prolonged stress are a few reasons why premature aging is very common these days.
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Skin Care Tips For Men

Every man’s skin is different, and there is no ‘one size fits all’ approach to skin care. When it comes to skin care, men have traditionally kept it simple. However, more men are now pursuing healthier, younger-looking skin, making it a great time for men to evaluate their skin care routine and learn more about how to take care of their body’s largest organ. Although there are key differences between men and women’s skin – for example, men’s skin is thicker than women’s – the basic elements of an effective skin care plan remain the same.
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S3 – The Frame® Integrative Functional Mix Supplement

The B-group vitamins are known as B1, B2, B3, B5, B6 and B12. Generally speaking, deficiencies are not related to a single vitamin of this group but to a deficiency in several vitamins, or a deficiency in one leading to deficiencies in other group-B vitamins. Vitamin B1, or Thiamine, is contained in brewer's yeast, whole grains, fresh and dried legumes, nuts and eggs. A deficiency causes polyneuritis and heart failure. Vitamin B2, or Riboflavin, is found above all in leafy greens, brewer's yeast, egg whites, milk and dairy products, and meat.
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Common Sense And Anti-Ageing Skincare

When it comes to skincare, all we really want to know is what works, how much it costs and where we can buy it. So why do so many of us feel overwhelmed by the choice of products and often confusing, not to mention conflicting, advice? It's one of the reasons why sales of skincare are not as strong as they were - and why women are choosing to stick with what they know works rather than investing in gimmicky 'miracle creams' that promise the earth and don't deliver.
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Your Age And Your Skin

Any beauty regimen should begin by taking good care of your skin. And the earlier that you begin to care for it, the better. This is so important as when we get older and use and abuse our bodies, the appearance and condition of our skin will begin to reflect our age and lifestyle. Skin tends to go through phases according to our age and if we know what to look out for, we can begin to take preventative steps to keep our skin looking it's best.
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Why Is Better To Use Organic Skin Care ?

There are many skin care product lines that are widely sold in the market place that are not safe. Many of these skin care products contain caustic chemicals, preservatives and many other additives that can cause not only skin reactions but can also lead to serious conditions both on your skin and for your overall health.
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Detoxifying And Purifying Frame® Cleansers

A perfect skin is not only a joy for the eyes. It is also a synonym of health and wellness! Skin imperfections, such as a shiny and/or fat skin, are caused by excess sebum, stress or dehydration, and can be healed with regular treatments that aim at constantly cleansing and moisturising your skin, favoring perspiration and nourishment. Every day our skin is exposed to countless external stressors - smoke, fumes and UVA/UVB rays. In fact, air particle pollution is now being linked to visible signs of skin damage (what the industry describe as {polluaging}), so it is practically impossible to avoid encountering toxins on a daily basis.
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